Stewart M
Equine Vet J. 1976 Jan;8(1):17-9. doi: 10.1111/j.2042-3306.1976.tb03276.x.
The structure of vertebrate skeletal muscle is reviewed. The mechanism of muscular contraction and its control is then discussed from the point of view of molecular structure. Contraction takes place by a sliding filament mechanism produced by cross-bridges which form between thick and thin filaments. Control is exercised by tropomyosin and troponin. When the calcium concentration is low, these proteins interfere with the formation of cross-bridges and prevent contraction, but when the calcium concentration is increased, they no longer interfere and contraction proceeds.
本文综述了脊椎动物骨骼肌的结构。然后从分子结构的角度讨论了肌肉收缩的机制及其控制。收缩是由粗细肌丝之间形成的横桥产生的滑行丝机制发生的。控制是由原肌球蛋白和肌钙蛋白行使的。当钙浓度较低时,这些蛋白质会干扰横桥的形成并阻止收缩,但当钙浓度增加时,它们不再干扰,收缩就会进行。