[诱导胸腺细胞凋亡的信号转导途径的多样性。bcl-2、pim-1、c-myc和p53基因在胸腺细胞选择过程中的作用]
[Diversity of signal transduction pathways which induce apoptosis of thymocytes. Role of bcl-2, pim-1, c-myc and p53 genes in selection processes of thymocytes].
作者信息
Matuszyk J, Strzadała L
机构信息
Laboratorium Immunologii Komórkowej Instytutu Immunologii i Terapii Doświadczalnej PAN we Wrocławiu.
出版信息
Postepy Hig Med Dosw. 1994;48(6):663-75.
PMID:7675728
Abstract
There are independent signaling pathways which transmit apoptotic signals in thymocytes. c-Myc and p53 proteins participate in the apoptosis induction, whereas Bcl-2 and Pim-1 proteins inhibit complex apoptotic machinery.
摘要
在胸腺细胞中存在传递凋亡信号的独立信号通路。c-Myc和p53蛋白参与凋亡诱导，而Bcl-2和Pim-1蛋白则抑制复杂的凋亡机制。
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