MMWR Morb Mortal Wkly Rep. 1993 Jun 18;42(23):456-9.
Pseudomonas cepacia (PC) is a multidrug-resistant, gram-negative bacillus that causes chronic colonization and infection of the respiratory tract of persons with cystic fibrosis (CF). PC colonization is usually difficult to eradicate with antimicrobial therapy and, in some patients, infection is associated with rapid decline in pulmonary function, increased hospitalization, and earlier death. Previous studies have suggested person-to-person transmission of PC both within and outside of hospitals. However, possible transmission of PC at CF summer camps--sites for physical and psychosocial therapy for many patients--has not been well characterized. To assess the risk for PC transmission in this setting, in 1987 and 1990, the CF Foundation and CDC conducted epidemiologic investigations in four CF summer camps in Michigan, Ohio, Utah, and Ontario, Canada. This report summarizes the results of these studies.
洋葱伯克霍尔德菌(PC)是一种耐多药革兰氏阴性杆菌,可导致囊性纤维化(CF)患者呼吸道的慢性定植和感染。PC定植通常难以通过抗菌治疗根除,在一些患者中,感染与肺功能迅速下降、住院次数增加和过早死亡有关。先前的研究表明,PC可在医院内外发生人际传播。然而,PC在CF夏令营(许多患者进行身体和心理社会治疗的场所)的可能传播情况尚未得到充分描述。为评估这种情况下PC传播的风险,1987年和1990年,CF基金会和疾病预防控制中心在密歇根州、俄亥俄州、犹他州和加拿大安大略省的四个CF夏令营进行了流行病学调查。本报告总结了这些研究的结果。