Pereira Júnior A, Volchan E, Bernardes R F, Rocha-Miranda C E
Programa de Neurobiologia, Universidade Federal do Rio de Janeiro, Brazil.
Exp Brain Res. 1994;102(2):327-38. doi: 10.1007/BF00227519.
In the present work, we characterize electrophysiologically a commissural subcortical pathway which is related to binocular interactions in the nucleus of the optic tract (NOT) of the opossum. The main role played by the circuit comprising this pathway seems to be in relaying information coming from the ipsilateral eye to the NOT. The strongest evidence comes from experiments in which lidocaine was injected into the NOT and the ensuing effects in the opposite nucleus were monitored under ipsilateral monocular stimulation. It was consistently observed that during action of lidocaine the directional response normally elicited by stimulation of the ipsilateral eye did not take place in the NOT opposite to the silenced nucleus. This effect was reverted in a few minutes after recovery of the injected NOT. The response to stimulation of the contralateral eye, though, was not affected by this procedure.
在本研究中，我们用电生理学方法对负鼠视束核（NOT）中与双眼相互作用相关的连合皮质下通路进行了表征。由该通路组成的回路所起的主要作用似乎是将来自同侧眼的信息传递到NOT。最有力的证据来自于将利多卡因注入NOT，并在同侧单眼刺激下监测对侧核随后产生的效应的实验。一致观察到，在利多卡因作用期间，同侧眼刺激通常引发的定向反应在与沉默核相对的NOT中并未发生。在注入的NOT恢复几分钟后，这种效应就会逆转。然而，对侧眼刺激的反应不受该操作的影响。
