Kanaya S, Kato H, Doke M, Okushiba S, Shimozawa E, Horita S
Second Department of Surgery, Hokkaido University of Medicine, Sapporo, Japan.
Nihon Geka Gakkai Zasshi. 1995 Feb;96(2):106-15.
The importance of unravel hemodynamics at the stomach and esophagus in patients with portal hypertension has been described for understanding pathophysiology and treatment of varices associated with portal hypertension. Microvascular Doppler sonogrlaphy (MF20) is a pulse Doppler method with 20 MHz which is able to measure velocity and direction of blood flow in microvessel. We invented transendoscopic microvascular Doppler sonography (EMDS) by connecting a tiny probe of one mm in diameter with an endoscopy. We evaluated direction of blood flow in the esophageal and gastric varices by EMDS and angiography in 21 untreated and 26 shunt-operated patients with portal hypertension. In all of untreated patients direction of blood flow in the varices was toward the probe (forward). Results obtained with EMDS were consistent with angiographic results available in 13 patients. Direction of blood flow after shunt operation was away from the probe in 21 out of 26 patients. The comparison with angiography revealed that post-operative patients with "away" blood flow in varices had maintained satisfactory shunt selectivity without hepatofugal collateral and it proved that the direction of blood flow was toward the shunt at lower pressure. In conclusion EMDS is useful as an evaluation method for hemodynamics in varices of the esophagus and stomach.
门静脉高压患者胃和食管血流动力学的研究对于理解门静脉高压相关静脉曲张的病理生理学和治疗具有重要意义。微血管多普勒超声(MF20)是一种20MHz的脉冲多普勒方法,能够测量微血管内血流的速度和方向。我们通过将直径为1mm的微型探头与内镜相连,发明了经内镜微血管多普勒超声检查(EMDS)。我们用EMDS和血管造影术评估了21例未经治疗和26例接受分流手术的门静脉高压患者食管和胃静脉曲张的血流方向。在所有未经治疗的患者中,静脉曲张内的血流方向朝向探头(正向)。EMDS的结果与13例患者的血管造影结果一致。26例患者中有21例分流手术后血流方向背离探头。与血管造影的比较显示,术后静脉曲张血流“背离”的患者保持了良好的分流选择性,没有肝外分流,这证明在较低压力下血流方向朝向分流。总之,EMDS可作为评估食管和胃静脉曲张血流动力学的一种有用方法。