Lu T, Li J, Hu Y
Cancer Hospital, Zhongshan Medical University, Guangzhou.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1994;29(5):295-8.
100 patients with destruction of skull base in nasopharyngeal carcinoma, confirmed by pathology and CT scanning before radiotherapy, were analysed. It showed that the primary characteristics of skull base destruction are headache and cranial nerve involvement. Although the destruction of skull base showed evident manifestation in TNM classification, it can be inferred that the erosion development probably took place within 1-6 months. Comparing the CT scanning with X-ray submento-vertical view, the result indicated that the erosions of the various positions of the skull base and the invasion of paranasal sinus, cavernous sinus and orbit were clearly displayed by CT scanning but only 23% was discovered by X-ray. There was significant difference between CT scanning and X-ray, and CT scanning had more advantages. The relation between the erosion of the skull base and the invasion of parapharynx space and the metastatics of the cervical nodes were also discussed.
对100例鼻咽癌颅底破坏患者进行分析，这些患者在放疗前经病理及CT扫描确诊。结果显示，颅底破坏的主要特征为头痛及脑神经受累。尽管颅底破坏在TNM分类中有明显表现，但可推断其侵蚀发展可能在1 - 6个月内发生。将CT扫描与X线颏顶位片进行比较，结果表明CT扫描能清晰显示颅底各部位的侵蚀以及鼻窦、海绵窦和眼眶的侵犯，而X线仅发现23%。CT扫描与X线之间存在显著差异，CT扫描具有更多优势。还讨论了颅底侵蚀与咽旁间隙侵犯及颈部淋巴结转移之间的关系。
