Low R N, Carter W D, Saleh F, Sigeti J S
Department of Diagnostic Radiology, Sharp Memorial Hospital, San Diego, CA 92123-2740, USA.
Radiology. 1995 May;195(2):391-400. doi: 10.1148/radiology.195.2.7724757.
To determine the accuracy of breath-hold gadolinium- and perflubron-enhanced magnetic resonance (MR) imaging, immunoscintigraphy with indium-111-CYT-103 (planar and single photon emission computed tomography [CT]), and contrast material-enhanced CT for the detection of ovarian cancer prior to laparotomy.
Sixteen patients with primary (n = 3) or treated (n = 13) ovarian cancer underwent imaging of the abdomen and pelvis with each modality. All images were reviewed prospectively for tumor location, and results were compared with findings at surgery.
With CT or MR imaging, tumor was detected in 11 of 13 (85%) patients compared with 11 of 12 patients (92%) with immunoscintigraphy. Per patient accuracy for CT was 81% compared with 75% for MR imaging and 86% for immunoscintigraphy. For detection of individual sites of tumor, the sensitivity of MR imaging was highest (81%) compared with CT (51%, P < .001) and immunoscintigraphy (50%, P < .01). The combination of MR imaging and immunoscintigraphy depicted 89% of sites of tumor involvement confirmed at laparotomy.
MR imaging and immunoscintigraphy show promise for the evaluation of patients with ovarian cancer.
确定屏气钆和全氟溴烷增强磁共振（MR）成像、铟-111-CYT-103免疫闪烁显像（平面和单光子发射计算机断层扫描[CT]）以及对比剂增强CT在剖腹手术前检测卵巢癌的准确性。
16例原发性（n = 3）或经治疗（n = 13）的卵巢癌患者接受了上述每种检查方法对腹部和盆腔的成像检查。所有图像均前瞻性地评估肿瘤位置，并将结果与手术所见进行比较。
CT或MR成像在13例患者中的11例（85%）检测到肿瘤，而免疫闪烁显像在12例患者中的11例（92%）检测到肿瘤。CT的每位患者准确率为81%，MR成像为75%，免疫闪烁显像为86%。对于肿瘤单个部位的检测，MR成像的敏感性最高（81%），高于CT（51%，P <.001）和免疫闪烁显像（50%，P <.01）。MR成像和免疫闪烁显像联合显示了剖腹手术证实的89%的肿瘤累及部位。
MR成像和免疫闪烁显像在评估卵巢癌患者方面显示出前景。
