经5-氟胞嘧啶治愈的多发性淋巴结隐球菌病
Multiple lymphonodular cryptococcosis, cured by 5-fluorocytosine.
作者信息
Tolentino P, Borrone C
出版信息
Scand J Infect Dis. 1976;8(1):61-4.
PMID:772795
Abstract
A 5-year-old boy was admitted with an acute febrile illness and painful and enlarged cervical lymph nodes. A chest X-ray showed right tracheobronchial lymph nodes. A lymph node biopsy demonstrated a tuberculoid appearance, with epitheloid cells, giant cells, and also necrotic zones. Cryptococcus neoformans was isolated both in culture and after animal inoculation. While amphotericin B was not tolerated by the patient, the oral administration of 5-fluorocytosine resulted in a rapid recovery.
摘要
一名5岁男孩因急性发热性疾病及颈部淋巴结疼痛肿大入院。胸部X线显示右气管支气管淋巴结肿大。淋巴结活检显示为结核样表现，可见上皮样细胞、巨细胞，还有坏死区域。在培养物及动物接种后均分离出新型隐球菌。患者无法耐受两性霉素B，但口服5-氟胞嘧啶后迅速康复。
相似文献
1
Multiple lymphonodular cryptococcosis, cured by 5-fluorocytosine.经5-氟胞嘧啶治愈的多发性淋巴结隐球菌病
Scand J Infect Dis. 1976;8(1):61-4.
2
Disseminated lymphonodular cryptococcosis treated with 5-fluorocytosine.
J Pediatr. 1979 Apr;94(4):599-601. doi: 10.1016/s0022-3476(79)80021-9.
3
Cryptococcus neoformans vertebral osteomyelitis.新型隐球菌性脊椎骨髓炎
J Med Vet Mycol. 1994;32(4):315-8.
4
Cryptococcal meningitis treated with 5-fluorocytosine and amphotericin B.用5-氟胞嘧啶和两性霉素B治疗的隐球菌性脑膜炎。
Isr J Med Sci. 1974 Sep;10(9):1148-52.
5
Disseminated infection with Cryptococcus neoformans var neoformans in an 8 years immunocompetent girl.一名8岁免疫功能正常女孩发生新型隐球菌新型变种的播散性感染。
Indian J Pediatr. 2005 Jan;72(1):85.
6
Isolated ocular cryptococcosis in an immunocompetent patient.免疫功能正常患者的孤立性眼部隐球菌病。
Ophthalmic Surg. 1992 Feb;23(2):129-31.
7
Primary abdominal lymphonodular cryptococcosis in children: 2 case reports and a literature review.儿童原发性腹部淋巴结隐球菌病：2例报告及文献复习
J Pediatr Surg. 2006 Mar;41(3):e11-5. doi: 10.1016/j.jpedsurg.2005.11.083.
8
Cryptococcosis with cutaneous manifestations treated with 5-fluorocytosine.
Dermatologica. 1980;161(5):327-33. doi: 10.1159/000250384.
9
Letter: Amphotericin B and 5-fluorocytosine.
J Infect Dis. 1975 Oct;132(4):489-90. doi: 10.1093/infdis/132.4.489.
10
Efficacy of amphotericin B in combination with flucytosine against flucytosine-susceptible or flucytosine-resistant isolates of Cryptococcus neoformans during disseminated murine cryptococcosis.两性霉素B联合氟胞嘧啶对播散性小鼠新型隐球菌病中氟胞嘧啶敏感或耐药分离株的疗效。
Antimicrob Agents Chemother. 2006 Jan;50(1):113-20. doi: 10.1128/AAC.50.1.113-120.2006.
Zotero 插件