尿路病原体中氨苄西林、头孢菌素和磺胺类耐药性的流行情况。

The prevalence of ampicillin, cephalosporin and sulphonamide resistance amongst urinary tract pathogens.

作者信息

Andrews J, Bywater M J, Emmerson A M, Keane C, Reeves D S, Wise R

出版信息

Scott Med J. 1976 Sep;20(5):232-5. doi: 10.1177/003693307502000511.

DOI:10.1177/003693307502000511

Abstract

A total of 2,031 clinical isolates of Gram negative bacilli was obtained from hospitals in 4 centres and these cultures were tested for resistance to ampicillin, cephazolin and sulphonamide. Ampicillin and sulphonamide resistance in outpatients ranged from 15 to 28 per cent of E. coli strains and 4 to 11 per cent of Proteus mirabilis strains. Resistance to cephazolin in outpatients ranged from 0 to 3 per cent of E. coli and 0 to 6 per cent of Proteus mirabilis. Resistance patterns for E. coli, Proteus mirabilis and Klebsiella strains isolated from inpatients were much higher and varied widely. These patterns are presented and the reasons for these variations discussed.

摘要

从4个中心的医院共获得2031株革兰氏阴性杆菌临床分离株，并对这些培养物进行了氨苄西林、头孢唑林和磺胺类药物的耐药性检测。门诊患者中，大肠杆菌菌株对氨苄西林和磺胺类药物的耐药率为15%至28%，奇异变形杆菌菌株为4%至11%。门诊患者中，大肠杆菌对头孢唑林的耐药率为0%至3%，奇异变形杆菌为0%至6%。从住院患者中分离出的大肠杆菌、奇异变形杆菌和克雷伯菌菌株的耐药模式要高得多，且差异很大。本文展示了这些模式，并讨论了这些差异的原因。