Br J Psychiatry. 1995 Feb;166(2):174-83.
Dysthymia has been reconceptualised in recent years from a personality disorder to a chronic affective disorder. It is incorporated into both the DSM and ICD diagnostic systems.
The members of the WPA Dysthymia Working Group combined the results of their manual literature searches with a search using Medline.
Available data are summarised under the headings of classification, epidemiology, validity, comorbidity, course and outcome, pharmacotherapy and psychotherapy. The coexistence of major depressive disorder, constituting 'double depression' is of particular importance.
Improved knowledge of this disorder has led to a more positive approach to treatment, in which antidepressants can usefully be complemented by psychosocial measures. A high proportion of cases remain unrecognised in most populations, leading to prolonged morbidity and distress, much of which is now treatable.
近年来,心境恶劣已从人格障碍重新概念化为慢性情感障碍。它被纳入《精神疾病诊断与统计手册》(DSM)和《国际疾病分类》(ICD)诊断系统。
世界精神病学协会(WPA)心境恶劣工作组的成员将他们手工文献检索的结果与使用医学主题词表(Medline)检索的结果相结合。
现有数据在分类、流行病学、效度、共病、病程与转归、药物治疗和心理治疗等标题下进行了总结。重度抑郁症的共存,即构成“双重抑郁”,尤为重要。
对这种疾病的深入了解已导致更积极的治疗方法,其中抗抑郁药可有效地辅以社会心理措施。在大多数人群中,很大一部分病例仍未被识别,导致发病期延长和痛苦加剧,而现在其中许多情况是可治疗的。