Seifert H, Blass G, Leetz H K, Voges M
University Hospital of Saarland, Institutes of Radiological Physics, Homburg/Saar, Germany.
Br J Radiol. 1995 Mar;68(807):301-5. doi: 10.1259/0007-1285-68-807-301.
For stable-xenon computed tomography (CT), an X-ray examination for measurement of cerebral blood circulation in the brain, the radiation exposure of the patient was determined in order to estimate the risk of inducing cancer. Organ doses of brain, eyelenses, thyroid and gonads have been calculated using the measured air kerma free-in-air on the axis of rotation and organ-specific conversion factors calculated with the Monte Carlo method. Dose measurements with TLD-100 rods using a humanoid Alderson phantom were carried out for verification of the calculated organ doses. In the case of brain partially located in the region of primary radiation a mean organ dose of 39 mSv was calculated. The dose measurements showed dose equivalents between 6 and 68 mSv in different regions of the brain and consequently an inhomogeneous dose distribution. From an estimation of the radiation-induced risk using the effective dose of 1.6 mSv it follows that one additional fatal cancer per 12,500 stable-xenon CT examinations has to be expected. The organ doses of eyelenses and thyroid located in the region of scattered radiation are so low that biological effects are hardly to be expected. The calculated dose equivalents of 6.5 mSv and 0.5 mSv, respectively, are in good agreement with measurements. The organ dose of gonads amounted to less than 0.07 mSv.
对于用于测量脑部脑血液循环的稳定氙计算机断层扫描(CT)这种X射线检查,测定了患者的辐射暴露量,以估计诱发癌症的风险。使用在旋转轴线上测得的空气比释动能自由空气值以及用蒙特卡罗方法计算的特定器官转换因子,计算了脑、眼晶状体、甲状腺和性腺的器官剂量。使用人形Alderson体模通过TLD - 100棒进行剂量测量,以验证计算出的器官剂量。对于部分位于原发射线区域的脑,计算出的平均器官剂量为39毫希沃特。剂量测量显示,脑的不同区域的剂量当量在6至68毫希沃特之间,因此剂量分布不均匀。根据使用1.6毫希沃特的有效剂量对辐射诱发风险的估计,每12,500次稳定氙CT检查预计会额外发生一例致命癌症。位于散射辐射区域的眼晶状体和甲状腺的器官剂量非常低,几乎不会产生生物学效应。计算出的剂量当量分别为6.5毫希沃特和0.5毫希沃特,与测量结果吻合良好。性腺的器官剂量小于0.07毫希沃特。