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鼻神经胶质瘤:真皮受累是否具有重要意义?

Nasal glioma: is dermis involvement significant?

作者信息

Thomson H G, al-Qattan M M, Becker L E

机构信息

Division of Plastic Surgery, Hospital for Sick Children, Ontario, Canada.

出版信息

Ann Plast Surg. 1995 Feb;34(2):168-72.

PMID:7741435
Abstract

Nasal gliomas are rare, benign, congenital masses more accurately referred to a sequestered glial tissue. Seven patients with nasal glioma treated by Hugh G. Thomson over the last 28 years are presented with special reference to tumor recurrence after excision and associated naso-ocular cleft. Three of our patients had an associated ipsilateral naso-ocular cleft, and three similar cases have been reported. This association is probably more frequent because a naso-ocular cleft can exist as a forme fruste and be easily overlooked. The first two tumors resected in our series recurred within 10 months; however, no recurrences were seen after a new treatment protocol was initiated in 1972. This consisted of total excision of the skin overlying the tumor if the skin adhered to the mass or if glial elements were seen within the dermis on frozen section. Deep resection margin was also assessed by frozen section of the nasal mucosa or fibrous stalk of the tumor. Accordingly, unnecessary intracranial procedures were avoided without increasing the risk of recurrence.

摘要

鼻胶质瘤是一种罕见的良性先天性肿块,更准确地说是一种隔离的神经胶质组织。本文介绍了休·G·汤姆森在过去28年中治疗的7例鼻胶质瘤患者,特别提及了切除术后的肿瘤复发情况以及相关的鼻眼裂。我们的3例患者伴有同侧鼻眼裂,另有3例类似病例已被报道。这种关联可能更为常见,因为鼻眼裂可能以不完全形式存在且容易被忽视。我们系列中最初切除的2例肿瘤在10个月内复发;然而,自1972年启动新的治疗方案后未再出现复发情况。该方案包括,如果覆盖肿瘤的皮肤与肿块粘连,或在冷冻切片的真皮内可见神经胶质成分,则将覆盖肿瘤的皮肤全部切除。还通过对鼻黏膜或肿瘤纤维蒂进行冷冻切片来评估深部切除边缘。据此,避免了不必要的颅内手术,同时并未增加复发风险。

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