Traub-Dargatz J L, McClure J J, Koch C, Schlipf J W
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
J Am Vet Med Assoc. 1995 Jan 1;206(1):67-70.
Four mule foals received anti-RBC antibody from their dam's colostrum. Two foals developed anemia, 1 developed severe thrombocytopenia, and 1 did not develop any clinical or laboratory abnormalities. All foals had the same donkey sire. Seven mares, including the dams of foals 1 to 4, bred to the donkey sire produced anti-RBC antibody. Two mares produced anti-RBC antibody to the donkey RBC on the first mating. The donkey sire and 18 of its offspring were found to have an RBC antigen unique to mules and donkeys. Thus, all matings of this donkey to horse mares were incompatible. The reason for the high rate of sensitization of mares bred to this donkey is unknown.
四头骡驹从其母马的初乳中获得了抗红细胞抗体。两头骡驹出现贫血，一头出现严重血小板减少症，还有一头未出现任何临床或实验室异常。所有骡驹都有同一个驴父亲。七匹母马，包括骡驹1至4的母马，与这头驴父亲交配后产生了抗红细胞抗体。两匹母马在首次交配时就产生了针对驴红细胞的抗红细胞抗体。这头驴父亲及其18个后代被发现有一种骡和驴特有的红细胞抗原。因此，这头驴与母马的所有交配都是不相容的。与这头驴交配的母马致敏率高的原因尚不清楚。
