Zornig C, Peiper M, Schröder S
Department of General Surgery, University Hospital Hamburg Eppendorf, Germany.
Br J Surg. 1995 Feb;82(2):278-9. doi: 10.1002/bjs.1800820247.
Between January 1988 and October 1993, 189 patients with soft tissue sarcoma of the extremities and trunk underwent surgery and since 1988, patients in whom the initial operation did not achieve safe margins underwent reoperation (67 of the 189). At re-excision an en block resection of the area with wide margins was achieved in 59 patients. Residual tumour was found in 30 specimens (45 per cent). Thirty-six patients received postoperative radiotherapy and/or chemotherapy. After a mean follow-up of 32 (range 1-69) months five patients (7 per cent) had local recurrence. In view of the high rate of local recurrence after local excision of soft tissue sarcoma (70-90 per cent), primary re-excision is indicated after an inadequate initial operation.
1988年1月至1993年10月期间,189例四肢及躯干软组织肉瘤患者接受了手术治疗,自1988年起,初始手术未达到安全切缘的患者接受了再次手术(189例中的67例)。再次切除时,59例患者实现了对该区域的整块广泛切除。30份标本(45%)中发现有残留肿瘤。36例患者接受了术后放疗和/或化疗。平均随访32个月(范围1 - 69个月)后,5例患者(7%)出现局部复发。鉴于软组织肉瘤局部切除后局部复发率较高(70% - 90%),初始手术不充分时应进行一期再次切除。