Critchley L A, Stuart J C, Short T G, Gin T
Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
Br J Anaesth. 1994 Oct;73(4):464-70. doi: 10.1093/bja/73.4.464.
We have studied the haemodynamic effects of subarachnoid block in elderly patients. Thirty patients were undergoing elective transurethral surgery and 18 non-elective orthopaedic surgery, predominantly fractured neck of femur. Systolic arterial pressure (SAP) was measured by automated oscillotonometry, central venous pressure (CVP) by manometer and cardiac index (CI), stroke index (SI) and heart rate (HR) by transthoracic electrical bioimpedance. Systemic vascular resistance index (SVRI) was derived. SAP decreased by more than 25% in 33 patients and SVRI showed similar decreases (P = 0.0001). CVP decreased (2.5 (SD 1.5) cm H2O) in all patients. CI was unaffected because a decrease in SI in some patients (13 (19)%; P = 0.01) was compensated for by an increase in HR (13 (13)%; P = 0.01). Decreases in SAP of 25% were treated initially with colloid solution 8 ml kg-1, which restored SAP in 19 patients. CVP, SI and HR were all restored to baseline values, however, SVRI was decreased further (P < 0.05). Fourteen patients required additional treatment with metaraminol which restored SVRI to baseline values. Patients with systolic hypertension were more likely to require treatment with metaraminol (P = 0.04).
我们研究了蛛网膜下腔阻滞对老年患者的血流动力学影响。30例患者接受择期经尿道手术,18例接受非择期骨科手术,主要是股骨颈骨折。采用自动示波法测量收缩压(SAP),用压力计测量中心静脉压(CVP),经胸电阻抗法测量心脏指数(CI)、每搏指数(SI)和心率(HR)。计算得出体循环血管阻力指数(SVRI)。33例患者的SAP下降超过25%,SVRI也有类似下降(P = 0.0001)。所有患者的CVP均下降(2.5(标准差1.5)cm H₂O)。CI未受影响,因为部分患者SI下降(13(19)%;P = 0.01)被HR升高(13(13)%;P = 0.01)所代偿。对于SAP下降25%的患者,最初给予8 ml/kg的胶体溶液治疗,19例患者的SAP得以恢复。CVP、SI和HR均恢复至基线值,然而,SVRI进一步下降(P < 0.05)。14例患者需要额外使用间羟胺治疗,使SVRI恢复至基线值。收缩期高血压患者更有可能需要间羟胺治疗(P = 0.04)。