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使用内镜多普勒设备对肠道血管发育异常出血进行诊断与治疗控制

Diagnosis and treatment control of bleeding intestinal angiodysplasias with an endoscopic Doppler device.

作者信息

Jaspersen D, Körner T, Schorr W, Brennenstuhl M, Hammar C H

机构信息

Medizinische Klinik II, Städtisches Klinikum, Fulda.

出版信息

Bildgebung. 1995 Mar;62(1):14-7.

PMID:7756818
Abstract

OBJECTIVE

To investigate the effectiveness of prophylactic injection therapy in vascular malformations after acute hemorrhage. To review recent advances in diagnosis and treatment control of bleeding intestinal angiodysplasias with an endoscopic Doppler device.

DESIGN

Open prospective study involving 34 patients with bleeding from gastroduodenal and colorectal angiodysplasias.

INTERVENTIONS

In order to detect the superficial arterial vessels responsible for the bleeding, a total of 79 lesions were scanned by transendoscopic Doppler ultrasonography. 70 vascular ectasias (88.6%) were Doppler-positive and had injection therapy with epinephrine and polidocanol.

RESULTS

Out of the 70 sclerosed angiodysplasias, 63% (90.0%) could not be found endoscopically 2 weeks later, confirming the success of therapy. Doppler noise was still recorded in 7 visible malformations, indicating insufficient treatment. Further injections were made into these lesions, and the vascular anomalies were finally eliminated. During 1 year of follow-up, 2 of the 34 treated patients (5.88%) relapsed with actively bleeding cecal angiodysplasias. After repeated endoscopic hemostasis, no more hemorrhage was observed in both patients. The results were partly published in previous publications.

CONCLUSION

Endoscopic Doppler ultrasonography may help in identification and treatment of intestinal angiodysplasias. The technically simple method allows objective evaluation of the endoscopic findings and enables monitoring of local endoscopic therapy.

摘要

目的

探讨预防性注射疗法对急性出血后血管畸形的疗效。综述使用内镜多普勒装置诊断和控制出血性肠道血管发育异常的最新进展。

设计

对34例胃十二指肠和结肠直肠血管发育异常出血患者进行的开放性前瞻性研究。

干预措施

为检测导致出血的浅表动脉血管,通过经内镜多普勒超声对总共79处病变进行扫描。70处血管扩张(88.6%)为多普勒阳性,并接受了肾上腺素和聚多卡醇注射治疗。

结果

在70处硬化的血管发育异常中,2周后内镜检查未发现63%(90.0%),证实治疗成功。7处可见畸形仍记录到多普勒噪声,表明治疗不充分。对这些病变进一步注射,最终消除了血管异常。在1年的随访中,34例接受治疗的患者中有2例(5.88%)因盲肠血管发育异常再次出血复发。经反复内镜止血后,两名患者均未再出血。部分结果已在之前的出版物中发表。

结论

内镜多普勒超声可能有助于肠道血管发育异常的识别和治疗。这种技术简单的方法可以客观评估内镜检查结果,并能够监测局部内镜治疗。

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