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实验性犬肺移植中的体外肺灌注(作者译)

[Extracorporeal lung perfusion in experimental canine lung transplantation (author's transl)].

作者信息

Grasshoff H J, Winsel K

出版信息

Z Erkr Atmungsorgane. 1975 Mar;142(3):294-300.

PMID:775814
Abstract

The present paper describes a simple method for the extracorporeal hypothermic perfusion of isolated lungs during the experimental lung transplantation in the dog. Two different solutions were used: sodium chloride-solution and Dextran-electrolyte-solution. The temperature of the perfused lung falls to 14 degrees C. The water-content is significantly increased by using the sodium chloride-solution, it is slightly increased after perfusion with Dextran-electrolyte solution. The total phospholipid-content is decreased in lungs perfused with sodium chloride-solution, it is significantly increased in lungs perfused with Dextran-electrolyte-solution.

摘要

本文描述了一种在犬实验性肺移植过程中对离体肺进行体外低温灌注的简单方法。使用了两种不同的溶液:氯化钠溶液和右旋糖酐电解质溶液。灌注肺的温度降至14摄氏度。使用氯化钠溶液时肺的含水量显著增加,用右旋糖酐电解质溶液灌注后含水量略有增加。用氯化钠溶液灌注的肺中总磷脂含量降低,而用右旋糖酐电解质溶液灌注的肺中总磷脂含量显著增加。

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