Guistini S, Mandelli P, Bartoli U, Pastacaldi G, Pasticci C, Fronges D, Quattrocchi M
Medici di Medicina Generale, USL N 8, SIMG Sezione di Pistoia.
Riv Eur Sci Med Farmacol. 1994 Jan-Apr;16(1-2):7-11.
This study follows a cognitive investigation about risk factor for ischemic heart disease performed in 1990 by a group of general practitioners in Pistoia, Italy. From this investigation we selected subjects with hypercholesterolemia; we also considered the association with other risk factors for ischemic heart disease. According to the frequency of risk factors subjects received a low-fat diet or diet plus cholesterol-lowering drug therapy (simvastatin). We describe changes on total cholesterol and its fractions by these therapeutic regimens.