Guistini S, Mandelli P, Bartoli U, Pastacaldi G, Pasticci C, Fronges D, Quattrocchi M
Medici di Medicina Generale, USL N 8, SIMG Sezione di Pistoia.
Riv Eur Sci Med Farmacol. 1994 Jan-Apr;16(1-2):7-11.
This study follows a cognitive investigation about risk factor for ischemic heart disease performed in 1990 by a group of general practitioners in Pistoia, Italy. From this investigation we selected subjects with hypercholesterolemia; we also considered the association with other risk factors for ischemic heart disease. According to the frequency of risk factors subjects received a low-fat diet or diet plus cholesterol-lowering drug therapy (simvastatin). We describe changes on total cholesterol and its fractions by these therapeutic regimens.
本研究遵循了1990年由意大利皮斯托亚的一组全科医生进行的关于缺血性心脏病危险因素的认知调查。从这项调查中,我们挑选了高胆固醇血症患者;我们还考虑了其与缺血性心脏病其他危险因素的关联。根据危险因素的出现频率,受试者接受低脂饮食或饮食加降胆固醇药物治疗(辛伐他汀)。我们描述了这些治疗方案对总胆固醇及其组分的影响。