Haris J P, Phillipson O T
Department of Psychology, University of Reading, Earley Gate, Whiteknights, UK.
Psychopharmacology (Berl). 1995 Feb;117(3):379-84. doi: 10.1007/BF02246113.
The anxiolytic lorazepam was studied for its effects on contrast sensitivity to gratings flickering in counterphase in normal volunteers. The drug significantly reduced contrast sensitivity at low spatial frequencies in a dose-related manner. The results are discussed with reference to possible GABA-mediated processes in the retina and lateral geniculate nucleus.
对正常志愿者研究了抗焦虑药劳拉西泮对反相闪烁光栅的对比敏感度的影响。该药物以剂量相关的方式显著降低了低空间频率下的对比敏感度。参照视网膜和外侧膝状核中可能的γ-氨基丁酸(GABA)介导的过程对结果进行了讨论。