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爱尔兰人群中的非黑色素瘤皮肤癌:风险因素评估

Nonmelanoma skin cancer in an Irish population: an appraisal of risk factors.

作者信息

Healy E, Collins P, Barnes L

机构信息

City of Dublin Skin & Cancer Hospital.

出版信息

Ir Med J. 1995 Mar-Apr;88(2):58-9.

PMID:7775148
Abstract

Previous Irish studies have shown a high prevalence of nonmelanoma skin cancer (NMSC). However, unlike elsewhere where the generally quoted ratio of basal cell carcinoma (BCC):squamous cell carcinoma (SCC) is at least 4:1 the ratio in Ireland was found to be 1:1. We examined this ratio in patients attending the dermatology outpatients and determined risk factors for the development of NMSC within an Irish population where 75% of the population have been shown to have skin type 1 or 11. The study consisted of a retrospective 10 year review of biopsy proven cases of NMSC and a prospective case control study of NMSC which allowed examination of risk factors and comparison to a control group. The BCC:SCC ratio in the retrospective study was 3:1. In the prospective study the ratio of BCC:SCC was 4.4:1. Skin type 1 and numerous freckles were identified as risk factors in the NMSC group.

摘要

爱尔兰以往的研究表明,非黑色素瘤皮肤癌(NMSC)的患病率很高。然而,与其他地方普遍引用的基底细胞癌(BCC)与鳞状细胞癌(SCC)的比例至少为4:1不同,爱尔兰的这一比例为1:1。我们对皮肤科门诊患者的这一比例进行了研究,并确定了爱尔兰人群中NMSC发病的风险因素,在该人群中,75%的人皮肤类型为1型或2型。该研究包括对经活检证实的NMSC病例进行为期10年的回顾性研究,以及对NMSC进行前瞻性病例对照研究,这使得能够检查风险因素并与对照组进行比较。回顾性研究中BCC与SCC的比例为3:1。在前瞻性研究中,BCC与SCC的比例为4.4:1。皮肤类型1和大量雀斑被确定为NMSC组的风险因素。

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