Kitada T, Seki S, Kawakita N, Kuroki T, Monna T
Department of Public Health, Osaka City University Medical School, Japan.
Biochem Biophys Res Commun. 1995 Jun 6;211(1):33-9. doi: 10.1006/bbrc.1995.1774.
We measured the telomere length in patients with chronic hepatitis or liver cirrhosis and found a significant telomere shortening in the liver with chronic liver disease compared to that in the normal liver. The telomere length tended to decrease with the progression of chronic liver disease.
我们测量了慢性肝炎或肝硬化患者的端粒长度,发现与正常肝脏相比,慢性肝病患者肝脏中的端粒显著缩短。端粒长度倾向于随着慢性肝病的进展而降低。