冠心病患者中不同的示踪剂和应激源：如何规范临床问题与核心脏病学的答案。

Different tracers and stressors in patients with coronary artery disease: how to standardize clinical questions and nuclear cardiology answers.

作者信息

Marzullo P, Sambuceti G, Gimelli A, Giorgetti A, Parodi O

机构信息

CNR Institute of Clinical Physiology, Pisa, Italy.

出版信息

J Nucl Biol Med (1991). 1994 Dec;38(4):566-72.

PMID:7786918

Abstract

The recent introduction of new tracers and stressors has increased the number of combinations of techniques that can be used for the diagnostic and prognostic stratification of patients with coronary artery disease. However, these new techniques still need to be standardized for clinical use. Thallium-201 scintigraphy is at present the most common method to assess transient ischemia and viability in patients. Dynamic exercise and dipyridamole show similar incidence of major cardiac complications and their use can be considered sufficiently safe. Further experimental and multicenter clinical studies are needed for 99mTc-Sestamibi and 99mTc-Teboroxime and for new stressors such as adenosine and dobutamine.

摘要

最近新型示踪剂和应激源的引入增加了可用于冠心病患者诊断和预后分层的技术组合数量。然而，这些新技术仍需进行临床应用标准化。铊-201闪烁扫描术目前是评估患者短暂性缺血和存活能力的最常用方法。动态运动和双嘧达莫显示出相似的严重心脏并发症发生率，其使用可被认为足够安全。对于99m锝-甲氧基异丁基异腈和99m锝-特丁基异腈以及诸如腺苷和多巴酚丁胺等新型应激源，还需要进一步的实验和多中心临床研究。