[锌缺乏生长大鼠的生长影响]

[Affection of growth of zinc deficiency growing rats].

作者信息

Zhao L, Eiderlsburg U, Eder K, Kirchgessner M

机构信息

Trace Elements Research Lab, Chinese PLA General Hospital, Beijing.

出版信息

Zhonghua Yi Xue Za Zhi. 1995 Apr;75(4):230-2, 256.

PMID:7788555

Abstract

Fifty male Sprague-Dawley rats with an average live mass of 42 +/- 4g were divided into 5 groups of 10 animals each. An artificial semi-systhesis diet was given to the animals. Group 1 received a control diet (32.2 mg Zn/kg DM), and group 2 a zinc deficient diet (3.4 mg Zn/kg DM) ad libitum. The animals of group 3 were pair fed to group 2 with a diet (84.9 mg Zn/KgDM). Diets of group 4 and 5 contained zinc (4.4 and 5.5 kg Zn/micrograms DM), respectively. The two groups also pair fed to group 2. The food intake and live mass gain were observed every day. After 26 days of experiment, the animals were decapitated; the blood samples were collected for the analysis of serum zinc, zinc binding capacity, and alkaline phosphatase.

摘要

选取50只平均体重为42±4克的雄性斯普拉格-道利大鼠，将其分为5组，每组10只。给这些动物喂食人工半合成饲料。第1组给予对照饲料（锌含量为32.2毫克/千克干物质），第2组给予锌缺乏饲料（锌含量为3.4毫克/千克干物质），任其自由采食。第3组动物与第2组配对饲养，饲料锌含量为84.9毫克/千克干物质。第4组和第5组饲料的锌含量分别为4.4微克/千克干物质和5.5微克/千克干物质，这两组也与第2组配对饲养。每天观察动物的采食量和体重增加情况。实验26天后，将动物断头；采集血液样本，用于分析血清锌、锌结合能力和碱性磷酸酶。