Dey H M, Soufer R
Nuclear Medicine Service, Veterans Affairs Medical Center, West Haven, CT, USA.
Eur J Nucl Med. 1995 Mar;22(3):237-42. doi: 10.1007/BF01081519.
Reverse redistribution (RR) of thallium-201 has been associated with both acute and healed myocardial infarction, and with recent thrombolysis. The physiologic basis for RR in coronary artery disease (CAD) is unclear but may be related to an admixture of viable and scarred myocardium within the RR segment. We performed thallium reinjection imaging at rest to better characterize RR defects in patients with chronic CAD. We found enhanced uptake of 201Tl in 52% of RR segments after reinjection, consistent with significant regional viability that was not evident on redistribution images. We then used a logistic multiple regression analysis to determine whether RR alone or in combination with other scintigraphic findings could predict patient outcome. The results showed that severe RR was an independent predictor of patient outcome. We conclude that RR may have prognostic significance in chronic CAD.
铊-201的反向再分布（RR）与急性和陈旧性心肌梗死以及近期溶栓治疗均有关联。冠状动脉疾病（CAD）中RR的生理基础尚不清楚，但可能与RR节段内存活心肌和瘢痕心肌的混合有关。我们进行了静息铊再注射显像，以更好地描述慢性CAD患者的RR缺损情况。我们发现再注射后52%的RR节段铊-201摄取增强，这与再分布图像上不明显的显著局部存活情况相符。然后我们使用逻辑多元回归分析来确定单独的RR或与其他闪烁显像结果联合是否能够预测患者的预后。结果显示严重RR是患者预后的独立预测因素。我们得出结论，RR在慢性CAD中可能具有预后意义。
