Lichodziejewska-Niemierko M, Niemierko J M, Malinowska A, Semetkowska-Jurkiewicz E, Manitius A, Rutkowski B
Klinika Chorób Nerek Akademii Medycznej w Gdańsku.
Pol Arch Med Wewn. 1994 Sep;92(3):223-7.
Blood-group antigens found on uroepithelial cells and in the secretions may affect bacterial adherence and thereby the predisposition to urinary tract infection. We determined P1, Lewis-blood-group phenotype and secretor status in patients with diabetes mellitus: 12 with asymptomatic bacteriuria and 7 without its presence. There was no difference between the two groups in the distribution of the P1 phenotype. There was also no statistical difference in the distribution of the Lewis phenotype and secretor status, although there appeared to be general trend of higher number of Le (a+b-) phenotype and non-secretors present in the asymptomatic bacteriuria group. Further studies are necessary to determine the role of blood groups and secretor status in the pathogenesis and susceptibility to urinary tract infection.
在上皮细胞和分泌物中发现的血型抗原可能会影响细菌黏附,进而影响尿路感染的易感性。我们测定了糖尿病患者的P1、Lewis血型表型和分泌状态:12例无症状菌尿患者和7例无此症状的患者。两组之间P1表型的分布没有差异。Lewis表型和分泌状态的分布也没有统计学差异,尽管在无症状菌尿组中似乎普遍存在Le(a+b-)表型和非分泌者数量较多的趋势。需要进一步研究以确定血型和分泌状态在尿路感染发病机制和易感性中的作用。