Langebaek J, Bay L
Scand J Dent Res. 1976 Jul;84(4):224-8. doi: 10.1111/j.1600-0722.1976.tb00483.x.
The purpose of this investigation was to evaluate the effect of 0.2% chlorhexidine gluconate mouthrinse following gingivectomy on plague under the dressing and on healing. Twenty-eight patients with indications for gingivectomy were selected. Coe-Pak was used as surgical dressing. In addition to unsual home care, the patients rinsed twice daily with chlorhexidine or placebo for 21 d after surgery. The study followed a cross-over double-blind design. Gingival exudate was assessed and Pl I and G I were registered at 7, 14, and 21 d postsurgically. The study indicated that chlorhexidine did not influence the amount of plaque under the dressing, and it was uncertain whether chlorhexidine had any effect on the healing process when the surgical area was covered by Coe-Pak. However, (1) after the surgical dressing was removed, the chlorhexidine maintained plaque scores at the same low level as under the dressing, (2) healing was was promoted when chlorhexidine was used, and (3) the presence of a dressing in one side of the mouth did not prevent the patient from maintaining good oral hygiene.
本研究的目的是评估牙龈切除术后使用0.2%葡萄糖酸氯己定漱口水对敷料下菌斑及愈合情况的影响。选取了28例有牙龈切除术指征的患者。Coe-Pak用作手术敷料。除常规家庭护理外,患者术后每天用氯己定或安慰剂漱口两次,持续21天。该研究采用交叉双盲设计。术后7天、14天和21天评估牙龈渗出液,并记录菌斑指数(Pl I)和牙龈指数(G I)。研究表明,氯己定不影响敷料下的菌斑量,当手术区域覆盖Coe-Pak时,氯己定是否对愈合过程有任何影响尚不确定。然而,(1)去除手术敷料后,氯己定能使菌斑评分维持在与敷料下相同的低水平,(2)使用氯己定时促进了愈合,(3)口腔一侧使用敷料并不妨碍患者保持良好的口腔卫生。