Mardh P A, Hovelius B, Nordenfelt E, Rosenberg R, Soltesz L V
Infection. 1976;4(1 Suppl):40-8. doi: 10.1007/BF01638422.
The incidence of respiratory tract infections in patients seeking medical advice at a community care centre (Dalby) during 1973 and 1974 was studied. About every third patient seen at this primary health station presented with signs of such infections. In the age groups less than 10, 10-19, 20-39, 40-59 and greater than or equal to 60 years, respiratory tract infections accounted for 65, 45, 32, 18 and 9% of the fotal number of diagnoses made during 1974. The aetiology of acute respiratory tract infections in a series of patients seen at this health station was studied. The series included randomly selected cases, but excluded children under seven years of age and patients presenting with signs of acute otitis media and tonsillitis. Attempts to establish the aetiology were made on the basis of the history, the clinical examination, and cultures for beta-haemolytic streptococci and Mycoplasma pneumoniae, complement foxation tests for influenza A and B, para-influenza 1, 2, and 3, adeno, cytomegalovirus and respiratory syncytial virus, and Chlamydia psittaci. Paul-Bunnell test and tests for cold agglutinins were also performed. With this test battery, an aetiological diagnosis was obtained in only 33% of the 101 patients studied. The findings suggest an infection with M.pneumoniae in 16%, with beta-haemolytic streptococci in 9%, and with viruses (adeno and para-influenza) in 7% of the patients. The present communication highlights the role of M.pneumoniae in upper respiratory infections, as few data have appeared on such infections in patients seen in general practice. The difficulty of establishing the aetiology of respiratory tract infections and the consequent treatment dilemma is discussed.
对1973年和1974年在一家社区护理中心(达尔比)寻求医疗建议的患者呼吸道感染发病率进行了研究。在这个初级保健站就诊的患者中,大约每三名患者就有一名有此类感染的迹象。在1974年,年龄小于10岁、10 - 19岁、20 - 39岁、40 - 59岁以及60岁及以上的年龄组中,呼吸道感染分别占所做诊断总数的65%、45%、32%、18%和9%。对在这个保健站就诊的一系列患者急性呼吸道感染的病因进行了研究。该系列包括随机选取的病例,但排除了7岁以下儿童以及有急性中耳炎和扁桃体炎迹象的患者。基于病史、临床检查、β - 溶血性链球菌和肺炎支原体培养、甲型和乙型流感、副流感1、2和3、腺病毒、巨细胞病毒和呼吸道合胞病毒的补体结合试验以及鹦鹉热衣原体检测来确定病因。还进行了嗜异性凝集试验和冷凝集素检测。通过这套检测方法,在研究的101名患者中,仅33%的患者获得了病因诊断。研究结果表明,16%的患者感染了肺炎支原体,9%感染了β - 溶血性链球菌,7%感染了病毒(腺病毒和副流感病毒)。本报告强调了肺炎支原体在上呼吸道感染中的作用,因为关于全科医疗中此类感染的资料很少。文中讨论了确定呼吸道感染病因的困难以及由此产生的治疗困境。