术后¹³¹I治疗对甲状腺癌患者随访中甲状腺球蛋白测量值的影响。

Effect of postoperative 131I treatment on thyroglobulin measurements in the follow-up of patients with thyroid cancer.

作者信息

Baskin H J

机构信息

Florida Thyroid and Endocrine Clinic (HJB), Orlando 32804.

出版信息

Thyroid. 1994 Fall;4(3):239-42. doi: 10.1089/thy.1994.4.239.

DOI:10.1089/thy.1994.4.239

PMID:7833657

Abstract

Correlation of serum thyroglobulin (Tg) levels with recurrent cancer was performed in 200 patients who had undergone a subtotal thyroidectomy for well-differentiated thyroid carcinoma. Patients were divided into three groups: (1) those not treated postoperatively with radioactive iodine, (2) those treated with low dose (30 mCi) radioactive iodine, and (3) those treated with high dose (50-250 mCi) radioactive iodine. Tg levels proved to be reliable in detecting recurrent thyroid cancer regardless of the dose of radioactive iodine given postoperatively. These results reinforce the recommendation of using the Tg assay as the primary method of following these patients postoperatively, even when there was less than a total thyroidectomy and ablation with radioactive iodine.

摘要

对200例行甲状腺次全切除术治疗分化型甲状腺癌的患者进行了血清甲状腺球蛋白（Tg）水平与复发癌的相关性研究。患者分为三组：（1）术后未接受放射性碘治疗的患者；（2）接受低剂量（30毫居里）放射性碘治疗的患者；（3）接受高剂量（50 - 250毫居里）放射性碘治疗的患者。结果表明，无论术后给予放射性碘的剂量如何，Tg水平在检测复发性甲状腺癌方面都是可靠的。这些结果强化了术后将Tg检测作为随访这些患者的主要方法的建议，即使甲状腺切除术未达到全切且未进行放射性碘消融。