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术后¹³¹I治疗对甲状腺癌患者随访中甲状腺球蛋白测量值的影响。

Effect of postoperative 131I treatment on thyroglobulin measurements in the follow-up of patients with thyroid cancer.

作者信息

Baskin H J

机构信息

Florida Thyroid and Endocrine Clinic (HJB), Orlando 32804.

出版信息

Thyroid. 1994 Fall;4(3):239-42. doi: 10.1089/thy.1994.4.239.

DOI:10.1089/thy.1994.4.239
PMID:7833657
Abstract

Correlation of serum thyroglobulin (Tg) levels with recurrent cancer was performed in 200 patients who had undergone a subtotal thyroidectomy for well-differentiated thyroid carcinoma. Patients were divided into three groups: (1) those not treated postoperatively with radioactive iodine, (2) those treated with low dose (30 mCi) radioactive iodine, and (3) those treated with high dose (50-250 mCi) radioactive iodine. Tg levels proved to be reliable in detecting recurrent thyroid cancer regardless of the dose of radioactive iodine given postoperatively. These results reinforce the recommendation of using the Tg assay as the primary method of following these patients postoperatively, even when there was less than a total thyroidectomy and ablation with radioactive iodine.

摘要

对200例行甲状腺次全切除术治疗分化型甲状腺癌的患者进行了血清甲状腺球蛋白(Tg)水平与复发癌的相关性研究。患者分为三组:(1)术后未接受放射性碘治疗的患者;(2)接受低剂量(30毫居里)放射性碘治疗的患者;(3)接受高剂量(50 - 250毫居里)放射性碘治疗的患者。结果表明,无论术后给予放射性碘的剂量如何,Tg水平在检测复发性甲状腺癌方面都是可靠的。这些结果强化了术后将Tg检测作为随访这些患者的主要方法的建议,即使甲状腺切除术未达到全切且未进行放射性碘消融。

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Effect of postoperative 131I treatment on thyroglobulin measurements in the follow-up of patients with thyroid cancer.术后¹³¹I治疗对甲状腺癌患者随访中甲状腺球蛋白测量值的影响。
Thyroid. 1994 Fall;4(3):239-42. doi: 10.1089/thy.1994.4.239.
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[Patients treated for differentiated thyroid cancer with negative 131I whole-body scans and elevated thyroglobulin levels: a possible course].分化型甲状腺癌患者经 131I 全身扫描阴性但甲状腺球蛋白水平升高:一种可能的病程
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Importance of postoperative stimulated thyroglobulin level at the time of 131I ablation therapy for differentiated thyroid cancer.分化型甲状腺癌131I消融治疗时术后刺激甲状腺球蛋白水平的重要性。
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Comparison of 800 and 3700 MBq iodine-131 for the postoperative ablation of thyroid remnant in patients with low-risk differentiated thyroid cancer.800与3700兆贝可碘-131用于低危分化型甲状腺癌患者术后甲状腺残余组织消融的比较
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A randomized clinical trial comparing 50mCi and 100mCi of iodine-131 for ablation of differentiated thyroid cancers.一项比较50毫居里和100毫居里碘-131用于分化型甲状腺癌消融的随机临床试验。
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The effects of radioactive iodine in thyroid remnant ablation and treatment of well differentiated thyroid carcinoma.放射性碘在甲状腺残余组织消融及分化型甲状腺癌治疗中的作用。
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Follow-up of low-risk differentiated thyroid cancer patients who underwent radioiodine ablation of postsurgical thyroid remnants after either recombinant human thyrotropin or thyroid hormone withdrawal.低危分化型甲状腺癌患者在重组人促甲状腺激素或甲状腺激素停药后行甲状腺残留术后碘-131 清甲治疗的随访。
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Preoperative undetectable serum thyroglobulin in differentiated thyroid carcinoma: incidence, causes and management strategy.分化型甲状腺癌术前血清甲状腺球蛋白检测不到:发生率、原因及管理策略
Clin Endocrinol (Oxf). 2007 Oct;67(4):547-51. doi: 10.1111/j.1365-2265.2007.02922.x. Epub 2007 Jun 11.

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