Diethelm A G, Sterling W A, Balch C M, Clark E C
Proc Clin Dial Transplant Forum. 1975 Nov;5:26-32.
The utilization of a hypothermic, hyperosmolar, intracellular washout solution for human kidney preservation was shown to be successful in 18 kidneys obtained from 9 heart beating cadavers. The ischemic interval ranged from 2 hrs and 57 mins to 39 hrs and 48 mins. All 18 kidneys functioned within 3 hrs of revascularization. Acute tubular necrosis with oliguria was noted in 4 of 6 patients with ischemic intervals longer than 20 hrs but not in the 12 patients obtaining kidneys preserved for 19 hrs or less. All patients with acute tubular necrosis required hemodialysis for one to 16 days post-transplantation with eventual recovery.
一种用于人类肾脏保存的低温、高渗、细胞内冲洗液，在取自9例心脏仍在跳动的尸体的18个肾脏上的应用被证明是成功的。缺血时间从2小时57分钟到39小时48分钟不等。所有18个肾脏在血管再通后3小时内开始发挥功能。在缺血时间超过20小时的6例患者中，有4例出现少尿型急性肾小管坏死，而在接受保存时间为19小时或更短的肾脏的12例患者中未出现。所有急性肾小管坏死患者在移植后均需进行1至16天的血液透析，最终恢复。
