Richieri-Costa A, Gorlin R J
Servico de Genética Clínica, Hospital de Pesquisa E. Reabiliticão de Lesões Lábio-Palatais, Universidade de São Paulo, Bauru, Brazil.
Am J Med Genet. 1994 Nov 15;53(3):222-6. doi: 10.1002/ajmg.1320530305.
Oblique facial clefts are rare and include types 2-6 of Tessier's classification. Here we report on 4 patients with oblique facial clefts and a strikingly similar facial appearance. The pattern of facial involvement, the presence of consanguinity in 3 of them, as well as the entire clinical picture, suggest a unique dysmorphogenetic process which could represent, in some instances, an oculomaxillofacial dysostosis.
斜面部裂很少见，包括泰西埃分类法中的2 - 6型。在此，我们报告4例斜面部裂患者，他们面部外观极为相似。面部受累模式、其中3例存在近亲结婚情况以及整体临床表现，提示存在一种独特的畸形发生过程，在某些情况下可能代表眼上颌面骨发育不全。
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