Ito T, Takahashi H, Ikuta F, Sato H
Department of Pathology, Niigata University, Japan.
Pathol Int. 1994 Dec;44(12):860-4. doi: 10.1111/j.1440-1827.1994.tb01685.x.
An unusual tumor in the spinal cord of a 57 year old man is reported. At the age of 42 years, the patient had had a pineal region tumor that subsequently disappeared completely after local radiation therapy only. Eleven and 15 years later, at the ages of 53 and 57 years, respectively, solitary spinal cord tumors were found and removed. Pathological examination revealed that these tumors were of neurogenic origin and showed the characteristic features of pineal parenchymal tumors such as pineocytoma and pineoblastoma. Based on the cytology of individual tumor cells and the absence of mitotic figures and necrotic foci, this patient was diagnosed as having metastatic pineocytoma of the spinal cord. This case suggests that distant, subarachnoidal metastasis to the spinal cord can occur in pineocytomas even after long-term dormancy.
报告了一名57岁男性脊髓中的一种罕见肿瘤。该患者42岁时患有松果体区肿瘤,仅经过局部放射治疗后肿瘤随后完全消失。11年和15年后,分别在53岁和57岁时发现并切除了孤立的脊髓肿瘤。病理检查显示这些肿瘤起源于神经源性,具有松果体实质肿瘤的特征,如松果体细胞瘤和松果体母细胞瘤。根据单个肿瘤细胞的细胞学特征以及无有丝分裂象和坏死灶,该患者被诊断为脊髓转移性松果体细胞瘤。该病例表明,即使经过长期休眠,松果体细胞瘤也可能发生远处蛛网膜下腔转移至脊髓。