乳酸——胚胎细胞分化的抑制因子。
Lactate--a suppressor of differentiation in embryonic cells.
作者信息
Løvtrup-Rein H, Landström U, Løvtrup S
出版信息
Cell Differ. 1978 Jun;7(3):131-8. doi: 10.1016/0045-6039(78)90013-1.
PMID:78767
Abstract
All kinds of visible differentiation in cultured amphibian embryonic cells are suppressed in the presence of lactate. This effect differs in certain respects from that observed with actinomycin, but like the latter lactate inhibits RNA synthesis. In this communication we present some further observations on the effect of lactate.
摘要
在乳酸存在的情况下，培养的两栖类胚胎细胞中的各种可见分化都会受到抑制。这种效应在某些方面与放线菌素所观察到的效应不同，但与放线菌素一样，乳酸会抑制RNA合成。在本通讯中，我们展示了关于乳酸效应的一些进一步观察结果。
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