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[甲状腺分化型癌的再次手术]

[Reoperation in differentiated carcinoma of the thyroid gland].

作者信息

Maffei Faccioli A, Pelizzo M R, Toniato A, Bernante P, Piotto A

机构信息

Istituto di Chirurgia Generale I, Università degli Studi, Padova.

出版信息

Chir Ital. 1994;46(4):59-60.

PMID:7882446
Abstract

A series of 112 patients reoperated on for differentiated thyroid cancer is analyzed; 60 patients (38 with papillary and 22 with follicular cancer) underwent ex-principio to completion of a non total thyroidectomy and 52 (37 with papillary and 15 with follicular cancer) to repeat surgery for local relapse. At a mean follow-up of 8.7 years, all the 38 patients with papillary cancer reoperated on for completion are alive and disease-free, while of those with follicular cancer 4 are dead, 2 are alive with carcinoma and 16 (72.7%) are disease free. A reoperation for relapse was performed on the thyroid in 11, on the thyroid and nodes in 23 patients (all had initially received partial thyroidectomy), and on nodes alone in 28 patients. At a mean follow-up of 10.2 years, 20 patients (54%) with papillary and 7 (46.6%) with follicular cancer are alive and disease-free, 8 patients with papillary and 1 with follicular cancer are alive with disease and the remainder are dead due to the tumour. Although there is no sure evidence that total thyroidectomy provides higher survival and fewer recurrences, since many factors, predominantly age influence the prognosis, total thyroidectomy is recommended as a minimal procedure to avoid less safe and less radical subsequent reoperation.

摘要

对112例因分化型甲状腺癌接受再次手术的患者进行了分析;60例患者(38例乳头状癌和22例滤泡状癌)最初接受非全甲状腺切除术并完成手术,52例(37例乳头状癌和15例滤泡状癌)因局部复发接受再次手术。平均随访8.7年,所有38例因完成手术而接受再次手术的乳头状癌患者均存活且无疾病,而滤泡状癌患者中4例死亡,2例带癌存活,16例(72.7%)无疾病。11例患者仅对甲状腺进行复发再次手术,23例患者对甲状腺和淋巴结进行再次手术(所有患者最初均接受部分甲状腺切除术),28例患者仅对淋巴结进行再次手术。平均随访10.2年,20例(54%)乳头状癌患者和7例(46.6%)滤泡状癌患者存活且无疾病,8例乳头状癌患者和1例滤泡状癌患者带癌存活,其余患者因肿瘤死亡。虽然没有确凿证据表明全甲状腺切除术能提供更高的生存率和更少的复发率,因为许多因素(主要是年龄)会影响预后,但建议将全甲状腺切除术作为一种最小化手术,以避免后续进行安全性较低和根治性较差的再次手术。

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