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在术前对肾血管转移瘤进行栓塞时,利用体感诱发电位预防缺血性神经损伤。

The use of somatosensory evoked potentials to prevent ischemic neural damage during preoperative embolization of a vascular renal metastasis.

作者信息

Dimar J R, Mehta S, Glassman S D, Puno R M, Johnson J R

机构信息

Department of Orthopaedic Surgery, University of Louisville School of Medicine, Kentucky.

出版信息

Orthop Rev. 1994 Dec;23(12):950-6.

PMID:7885726
Abstract

Tumors at the spinal cord level present challenging surgical problems. Hypernephromas and other tumors may have copious bleeding at the time of resection. This bleeding can be reduced by preoperative embolization resulting in a dramatic decrease in surgical morbidity. However, embolization does carry a risk of spinal cord infarction and resultant neurologic injury. To monitor this, somatosensory evoked potentials (SSEPs) were evaluated during embolization, with a resultant termination of the procedure after significant SSEP changes and clinical symptoms indicated cord ischemia. The SSEP readings normalized 24 hours later, by the time of surgical resection. We present a relevant case history and review of the literature on this subject. Clearly, SSEPs, and in the future, motor evoked potentials (MEPs), serve as a valuable adjunct to monitoring spinal cord function during embolization and may prevent preoperative ischemic injury.

摘要

脊髓水平的肿瘤带来了具有挑战性的外科手术问题。肾细胞癌和其他肿瘤在切除时可能会大量出血。术前栓塞可减少这种出血,从而显著降低手术并发症的发生率。然而,栓塞确实存在脊髓梗死及由此导致神经损伤的风险。为对此进行监测,在栓塞过程中对体感诱发电位(SSEPs)进行了评估,当SSEPs出现显著变化且临床症状表明脊髓缺血时,终止了该操作。手术切除时,SSEP读数在24小时后恢复正常。我们展示了一个相关病例并回顾了关于该主题的文献。显然,SSEPs以及未来的运动诱发电位(MEPs),在栓塞过程中作为监测脊髓功能的有价值辅助手段,可能预防术前缺血性损伤。

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