Cavagni G, Plebani A, Restani P, Marini S, Gardenghi M, Poiesi C, Duse M, Ugazio A G
Dipartimento Materno Infantile e Tecniche Biomediche, Università degli Studi di Brescia, Italia.
Pediatr Med Chir. 1994 Sep-Oct;16(5):413-9.
Cow's milk protein is quite commune in infancy (2-3% in first year of age). Casein, beta-lactoglobulin and alpha-lactalbumin are the main allergens of cow's milk. The authors describe the immunological reaction involved in IgE synthesis and consequential inflammation after ingestion of cow's milk proteins and present soy and protein extensive hydrolysates as alternative diets for children with cow's milk allergy. Moreover, the authors present their studies on immunogenicity of hydrolysed formulae. At the end they suggest the therapeutic strategy in the cow's milk protein allergy.
牛奶蛋白在婴儿期相当常见(一岁以内占2-3%)。酪蛋白、β-乳球蛋白和α-乳白蛋白是牛奶的主要过敏原。作者描述了摄入牛奶蛋白后参与IgE合成及随之而来的炎症的免疫反应,并提出大豆和深度水解蛋白作为牛奶过敏儿童的替代饮食。此外,作者介绍了他们关于水解配方奶粉免疫原性的研究。最后,他们提出了牛奶蛋白过敏的治疗策略。