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308纳米准分子激光治疗颞下颌关节结构——一项体外研究

Treatment of temporomandibular joint structures by 308-nm excimer laser--an in vitro investigation.

作者信息

Liesenhoff T, Funk A

机构信息

Klinik und Poliklinik für Mund-Kiefer-Gesichtschirugie, Technischen Universität München, Germany.

出版信息

Int J Oral Maxillofac Surg. 1994 Dec;23(6 Pt 2):425-7. doi: 10.1016/s0901-5027(05)80037-2.

Abstract

Arthroscopy of the temporomandibular joint (TMJ) has become a clinically important and increasingly accepted method for diagnosis and treatment of TMJ alteration. This minimally invasive method is clearly limited by the anatomic dimensions of the TMJ. The 308-nm excimer laser has already found clinical applications in angioplasty, ophthalmology, and dentistry. This study aimed to find out whether it is possible to ablate TMJ-related structures under arthroscopic conditions. It also aimed to determine the energy threshold for ablation and the maximum rate of ablation. By histologic investigation of the irradiated tissues, the amount of tissue alteration was determined. TMJ structures of freshly slaughtered pigs served as tissue samples. The 308-nm excimer laser light was guided through optical fibers. The tissue was irradiated under continuous flow of saline solution. The energy threshold for ablation of TMJ structures was found at about 1 J/cm2. The maximum rate of ablation was found at 3-5 micron/pulse, depending on the type of tissue. The amount of tissue alteration varied between 1 and 150 microns. The types of tissue alteration were vacuolization and hyalinization. The results of the investigations described indicate that the 308-nm excimer laser is an ideal tool for TMJ arthroscopic surgery. Unlike other laser systems, it offers a unique combination of minimal tissue alteration, precise tissue ablation, guidability through optical fibers, and good transmission through water. This makes possible endoscopic removal of free bodies, adhesions, exostoses, and appositions in a minimally invasive surgical procedure.

摘要

颞下颌关节(TMJ)镜检已成为诊断和治疗TMJ病变的一种临床上重要且越来越被认可的方法。这种微创方法明显受到TMJ解剖尺寸的限制。308纳米准分子激光已在血管成形术、眼科和牙科领域得到临床应用。本研究旨在探究在关节镜条件下是否有可能消融与TMJ相关的结构。它还旨在确定消融的能量阈值和最大消融速率。通过对辐照组织的组织学研究,确定组织改变的程度。刚屠宰的猪的TMJ结构用作组织样本。308纳米准分子激光通过光纤传导。在生理盐水持续流动的情况下对组织进行辐照。发现TMJ结构消融的能量阈值约为1焦耳/平方厘米。最大消融速率为3 - 5微米/脉冲,这取决于组织类型。组织改变的程度在1至150微米之间变化。组织改变的类型有空泡化和玻璃样变。所述研究结果表明,308纳米准分子激光是TMJ关节镜手术的理想工具。与其他激光系统不同,它具有组织改变最小、组织消融精确、可通过光纤引导以及在水中良好传输等独特组合。这使得在微创外科手术中能够通过内镜去除游离体、粘连、骨赘和附着物成为可能。

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