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[骨质疏松症危险因素与骨密度的相关性研究]

[Study on the association between risk factors for osteoporosis and bone mineral density].

作者信息

Miyamura T, Yamagata Z, Iijima S, Asaka A

机构信息

Department of Health Sciences, Yamanashi Medical University.

出版信息

Nihon Koshu Eisei Zasshi. 1994 Dec;41(12):1122-30.

PMID:7894064
Abstract

The relationship between bone mineral density (BMD) and risk factors for osteoporosis was investigated on 146 females (23-68 years old) in Enzan city, Yamanashi prefecture. BMD was measured by DEXA (Dual Energy X-ray Absorptiometry) method. Information regarding menstruation, health status, life-style, quantities of nutrient intake and frequencies of food intake were obtained by questionnaire. Fitness level was determined by exercise test and daily energy expenditure by calorie-counter. The results were as follows; 1) No relationship between physical activities or daily energy consumption and BMD was found. 2) No relationship between calcium intake or vitamin D intake and BMD was found, but a significant and positive correlation coefficient between intake frequency of milk products and BMD was observed. 3) Significant influences of age, BMI, presence of lumbago and food frequency score on BMD were indicated by multiple regression analysis. Food frequency score were defined as values weighted in each of three food category, obtained by factor analysis. 4) Significant influences of height decrement rate per year and number of years postmenopausal on BMD reduction rate per year were indicated by multiple regression analysis. These results suggest that these significant factors are useful in indications of risk for osteoporosis.

摘要

对山梨县富士吉田市146名年龄在23至68岁之间的女性,研究了骨密度(BMD)与骨质疏松症风险因素之间的关系。采用双能X线吸收法(DEXA)测量骨密度。通过问卷调查获取有关月经、健康状况、生活方式、营养素摄入量和食物摄入频率的信息。通过运动测试确定体能水平,并用卡路里计数器测定每日能量消耗。结果如下:1)未发现体育活动或每日能量消耗与骨密度之间存在关联。2)未发现钙摄入量或维生素D摄入量与骨密度之间存在关联,但观察到乳制品摄入频率与骨密度之间存在显著正相关系数。3)多元回归分析表明年龄、体重指数、腰痛的存在和食物频率得分对骨密度有显著影响。食物频率得分是通过因子分析在三个食物类别中加权得到的值。4)多元回归分析表明每年身高下降率和绝经后年限对每年骨密度降低率有显著影响。这些结果表明,这些显著因素有助于指示骨质疏松症风险。

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