[Mitochondrial DNA RFLP in inhabitants of Magadan].

Analysis of restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) from placenta tissue of Slavs living in Northern-East Asia is presented. BamHI, HpaI, EcoRV, and PvuII restriction endonucleases are used for this analysis (N = 40-50 for some restriction endonucleases). Combination of mtDNA types characteristic for distinct Mongoloid and Europeoid populations was found in a sample. HpaI-1 morph (Mongoloid marker) frequency is equal to 1.9% and BamHI-3 morph (Europeoid marker) frequency is equal to 2.5%. The sample investigated is monomorphic by PvuII endonuclease cleavage patterns. EcoRV-2 morph frequency exceeds 10%. Peculiarities of mtDNA restriction type structure in Magadan Region population are discussed in connection with a character of forming of Siberia and Far East population.