Bachmann G, Pfeifer T, Bauer T
Röntgenabteilung Innere Medizin, Justus-Liebig-Universität, Giessen.
Rofo. 1994 Sep;161(3):214-9. doi: 10.1055/s-2008-1032524.
A prospective study on 29 patients with presacral lesions after operation of rectal cancer was performed to define the accuracy of CT using a dynamic contrast study and MRI for detection of tumour recurrence (sensitivity) and differentiation from scar formation (specificity). In dynamic CT sensitivity was 88% and specificity was 100%. In MRI the respective data were 94% (sensitivity) and 92% (specificity). Additionally 14 patients with primary rectal cancer were included to define standards for dynamic CT; no differences between primary tumour and relapse were found. In MRI the assessment of signal intensities in T2w images permits differentiation between tumour relapse and scar tissue. In dynamic CT automatically calculated time-density graphs enable differentiation of presacral lesions and the initial increase of density after standardised bolus application was shown to be the most reliable parameter.
对29例直肠癌术后骶前病变患者进行了一项前瞻性研究,以确定使用动态对比研究的CT和MRI检测肿瘤复发的准确性(敏感性)以及与瘢痕形成相鉴别的准确性(特异性)。动态CT的敏感性为88%,特异性为100%。MRI的相应数据分别为94%(敏感性)和92%(特异性)。另外纳入了14例原发性直肠癌患者以确定动态CT的标准;未发现原发性肿瘤与复发之间存在差异。在MRI中,通过T2加权图像上信号强度的评估可区分肿瘤复发与瘢痕组织。在动态CT中,自动计算的时间-密度曲线能够区分骶前病变,标准化团注后密度的初始增加被证明是最可靠的参数。