Complexoproductive and antiheparin properties of low density lipoproteins (LDL). V. Optimum conditions of the coagulation method to determine antiheparin activity in the blood plasma.

It was found that storing the plasma in the temperature 0 degree C, 4 degrees C and 20 degrees C and especially in 37 degrees C increases pH and decreases antiheparin activity estimated by the heparin-thrombin test. Measurements of the heparin-thrombin time should be carried out directly after obtaining the plasma or after reducing the plasma to pH 7.40.