Susano R, Caminal L, Ferro J, Rubiales A, de Lera J, de Quirós J F
Servicio de Medicina Interna, Hospital Central de Asturias (Centro Universitario), Oviedo.
Rev Clin Esp. 1994 Aug;194(8):603-6.
From January of 1990 to June of 1993 a diagnosis of microangiopathic hemolytic anemia (MHA) was made in 5 out off 121 new patients with malignant tumor. There were 3 females and 2 males, with a mean age of 57 yr (range: 43-75), and a primary tumor in stomach (n = 2), pancreas (n = 1) and of unknown origin (n = 2). In all cases histologic type was adenocarcinoma and diagnosis was obtained by marrow examination. Four patients developed a disseminated intravascular coagulation syndrome. Intravascular deposits of fibrin, intimal proliferation and tumoral microembolisms were noted in 2 cases. Patients did not received chemotherapy, and the median survival was 7 days (range: 3-61).
1990年1月至1993年6月期间，121例新发恶性肿瘤患者中有5例被诊断为微血管病性溶血性贫血（MHA）。其中女性3例，男性2例，平均年龄57岁（范围：43 - 75岁），原发肿瘤位于胃（2例）、胰腺（1例）及来源不明（2例）。所有病例的组织学类型均为腺癌，诊断通过骨髓检查获得。4例患者发生了弥散性血管内凝血综合征。2例患者出现了血管内纤维蛋白沉积、内膜增生和肿瘤微栓子。患者未接受化疗，中位生存期为7天（范围：3 - 61天）。
