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[Design of heterologous mitochondria: import of cattle cytochrome P-450SCC precursors in plant mitochondria].

作者信息

Luzikov V N, Novikova L A, Spiridonova V A, Isaeva L V, Whelan J, Hugosson M, Glaser E

出版信息

Biokhimiia. 1994 Jul;59(7):1098-101.

PMID:7948418
Abstract

It has been shown that pre-P-450scc of bovine adrenal cortex mitochondria synthesized in a rabbit reticulocyte lysate cell-free system, is translocated into isolated soybean cotyledon mitochondria, thereby taking the mature form size. This finding is suggestive of the occurrence of a specific receptor and maturase for pre-P-450scc in plant mitochondria. Thus, plant mitochondria can be used as recipients for the mammalian cholesterol hydroxylase system in an attempt to study the mechanism of its formation and preservation.

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