Reversible neurotoxicity of interleukin-2 and tumor necrosis factor: correlation of SPECT with neuropsychological testing.
作者信息
Meyers C A, Valentine A D, Wong F C, Leeds N E
机构信息
Department of Neuro-Oncology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
出版信息
J Neuropsychiatry Clin Neurosci. 1994 Summer;6(3):285-8. doi: 10.1176/jnp.6.3.285.
PMID:7950353
Abstract
A 41-year-old man developed subacute neurotoxicity associated with interleukin-2 and tumor necrosis factor therapy for metastatic renal cell carcinoma. Cognitive deficits revealed on neuropsychological testing and frontal lobe perfusion deficits revealed on SPECT resolved after 1 month. Findings suggest possible neuroanatomic and physiologic substrates of cytokine neurotoxicity.
摘要
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