Williams S C, Peller P J
Department of Radiology, Walter Reed Army Medical Center, Washington, DC 20307.
Clin Nucl Med. 1994 Aug;19(8):668-70.
Extracolonic manifestations of Gardner's syndrome are common and may precede the detection of colonic polyps. Tc-MDP bone scintigraphy performed on a patient with Gardner's syndrome demonstrated intense uptake of radiotracer within the maxilla and mandible as a result of the dental anomalies associated with this disorder. Nuclear scintigraphy has a role in the imaging of these patients for skeletal anomalies, the detection of thyroid carcinoma, and for skeletal metastases when colon carcinoma is detected.
加德纳综合征的结肠外表现很常见,可能先于结肠息肉的发现。对一名加德纳综合征患者进行的锝-亚甲基二膦酸盐(Tc-MDP)骨闪烁显像显示,由于该疾病相关的牙齿异常,上颌骨和下颌骨内有强烈的放射性示踪剂摄取。核闪烁显像在这些患者的骨骼异常成像、甲状腺癌检测以及结肠癌被检测出时的骨转移检测中发挥作用。