Schlenker W, Looi E, Engström C, Walters R
Department of Orthodontics, Loma Linda University, CA 92350.
J Oral Maxillofac Surg. 1994 Dec;52(12):1273-8. doi: 10.1016/0278-2391(94)90050-7.
To investigate the mandibular growth pattern in rats during adolescence after altering the position of the mandible in the frontal plane instanteously by two surgical procedures.
Mandibular morphology during growth was recorded by cephalometric methods during the 3-week experimental period.
All procedures tested caused an altered mandibular morphology. An overall change was found in the shape of the mandible in the experimental groups, with the jaw being more square compared with the rectangular form found for the mandible in the control group. Condylar growth was abnormal and the cartilage of the experimental groups showed a reduced thickness and distorted morphology, indicating disturbed cellular activity.
In view of the findings, it was concluded that considerations to instantaneously alter the mandibular position during adolescence may not be advisable.
通过两种外科手术即时改变大鼠下颌骨在额平面的位置,研究青春期大鼠的下颌骨生长模式。
在为期3周的实验期内,采用头影测量法记录生长过程中的下颌骨形态。
所有测试的手术均导致下颌骨形态改变。实验组下颌骨形状出现整体变化,与对照组下颌骨的长方形形态相比,实验组下颌骨更呈方形。髁突生长异常,实验组软骨厚度减小且形态扭曲,表明细胞活动受到干扰。
鉴于这些发现,得出结论:在青春期即时改变下颌骨位置的做法可能不可取。