Gargani G
Ann Sclavo. 1976 Mar-Apr;18(2):281-5.
The large number of fungous strains isolated from specimens coming from the respiratory tract is a possible source of diagnostic failures. For an accurate diagnosis it is necessary to screen between fungi in a saprophitic and in a parasitic position. This is very difficult both for fungi, which are largely spread in the environment, like Aspergillus sp., and for fungi, which are commonly found on the mucous membranes, like Candida or Torulopsis sp. The actual pathogenetic activity of a fungous strain may be established on a mycological approach by means of an accurate taxonomic definition: only few species have pathogenetic possibilities: f.i. A. fumigatus, C. albicans. For a clinical-immunological approach are very useful the presence of debilitating diseases and the defectiveness of immunological tests, especially those of delayed hypersentivitity.
从呼吸道标本中分离出的大量真菌菌株可能是诊断失败的一个原因。为了准确诊断,有必要区分腐生状态和寄生状态的真菌。对于像曲霉菌属那样在环境中广泛传播的真菌,以及像念珠菌属或球拟酵母菌属那样常见于粘膜的真菌来说,做到这一点都非常困难。可以通过精确的分类学定义,采用真菌学方法来确定真菌菌株的实际致病活性:只有少数物种具有致病可能性,例如烟曲霉、白色念珠菌。存在使人虚弱的疾病以及免疫检测缺陷,尤其是迟发型超敏反应检测的缺陷,对于临床免疫学方法非常有用。