体内和体外类过敏麻醉反应中嗜酸性粒细胞阳离子蛋白（ECP）的释放
Release of eosinophil cationic protein (ECP) in anaphylactoid anaesthetic reactions in vivo and in vitro.
作者信息
Assem E S
机构信息
University College London, UK.
出版信息
Agents Actions. 1994 Jun;41 Spec No:C11-3. doi: 10.1007/BF02007745.
PMID:7976792
Abstract
In patients with anaphylactoid reactions (AR) to neuromuscular blocking drugs (NMB), eosinophil cationic protein (ECP) was released both in vivo and in vitro, and in IgE-dependent and IgE-independent reactions. Thus, eosinophils may play a role in both types of reactions, and ECP release tests may be of value in the diagnosis and study of the mechanism of AR.
摘要
在对神经肌肉阻滞药物（NMB）发生类过敏反应（AR）的患者中，嗜酸性粒细胞阳离子蛋白（ECP）无论在体内还是体外，以及在IgE依赖和IgE非依赖反应中都会释放。因此，嗜酸性粒细胞可能在这两种反应中都发挥作用，而ECP释放试验可能对AR的诊断和机制研究有价值。
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