Feliciano D V, Bitondo-Dyer C G
Department of Surgery, Emory University School of Medicine, Atlanta, Georgia.
Am J Surg. 1994 Dec;168(6):680-3; discussion 683-4. doi: 10.1016/s0002-9610(05)80144-8.
The clinical value of an elevated white blood cell (WBC) count on a diagnostic peritoneal lavage (DPL) performed in an asymptomatic patient with a penetrating abdominal stab wound is controversial.
We performed a comprehensive analysis of asymptomatic patients (no signs of peritonitis) with stab wounds who underwent an exploratory laparotomy based solely on a WBC count > 500/mm3 in the effluent of an open DPL.
Twenty-eight patients, 25 with injury to the gastrointestinal (GI) tract and 3 with injury to the liver, obtained true-positive results from DPL. Their mean WBC count in lavage effluent obtained at a mean of 7.6 hours after the stab wound was 3,380/mm3 and their mean serum WBC count, obtained at the same time, was 12,324/mm3. Fifteen patients had false-positive results from DPL. They were lavaged at a mean of 7.2 hours after the stab wound, and had a mean lavage WBC count of 1,228/mm3 and a mean serum WBC count of 9,084/mm3.
Patients lavaged at a mean 6 to 7 hours after an abdominal stab wound will have a significant incidence of false-positive studies based on an elevated WBC count alone. Lavage WBC counts > 3,000/mm3, particularly when associated with a serum WBC count > 11,000, are likely to be true positives and to indicate injury to the GI tract.
对于无症状的腹部刺伤患者,诊断性腹腔灌洗(DPL)时白细胞(WBC)计数升高的临床价值存在争议。
我们对仅基于开放DPL流出液中WBC计数>500/mm³而接受剖腹探查的无症状刺伤患者进行了全面分析。
28例患者中,25例胃肠道(GI)损伤,3例肝脏损伤,DPL结果为真阳性。刺伤后平均7.6小时获得的灌洗流出液中,他们的平均WBC计数为3380/mm³,同时获得的平均血清WBC计数为12324/mm³。15例患者DPL结果为假阳性。他们在刺伤后平均7.2小时接受灌洗,灌洗WBC平均计数为1228/mm³,血清WBC平均计数为9084/mm³。
腹部刺伤后平均6至7小时接受灌洗的患者,仅基于WBC计数升高会有显著的假阳性发生率。灌洗WBC计数>3000/mm³,特别是与血清WBC计数>11000相关时,可能为真阳性并提示GI tract损伤。