Liverani A, Chiarot M, Bezzi M, Angelini L
Cattedra di Chirurgia Generale, Università degli Studi di Roma La Sapienza.
Minerva Chir. 1994 Sep;49(9):747-50.
Of the numerous factors which may cause postoperative complications, some authors sustain that the durations of surgery plays a fundamentally important role. On the basis of a retrospective survey and analysis of cases operated, the authors observe that this factor, if considered alone, does not appear to cause a significant increase in septic complications, anastomotic dehiscence or mean postoperative hospital stay. Four homogeneous groups of patients were examined. Two groups included 100 who had undergone abdominal surgery which had not contaminated the peritoneal cavity. The other two groups included 150 patients who had undergone partially polluting colorectal surgery. The general preparation of patients was similar, with the exception of antibiotic prophylaxis. The mean time was calculated by analysing anesthesiological records. From an analysis of the most recent data, which are characterized by the absence of anastomotic dehiscence and operative mortality, it can be seen that the incidence of sepsis has fallen to 4% even if mean operating time was long. Mean postoperative hospital stay was also reduced from 17.3 days to 13 days. The prolongation of operating times does not depend on the complexity of surgery, intraoperative complications or the surgeon's inexperience, but may be the result of the meticulous implementation of procedures and steps taken to prevent complications which, given that they require extreme care and attention, necessarily contribute to increasing the duration of surgery. With regard to antibiotic prophylaxis and the duration of surgery, it was observed that if antibiotic prophylaxis preceded the operation by more than one hour, the incidence of sepsis was about 20%. If treatment coincided with the induction of anesthesia or the start of surgery, then the incidence of sepsis fell to 13%.(ABSTRACT TRUNCATED AT 250 WORDS)
在众多可能导致术后并发症的因素中,一些作者认为手术时长起着至关重要的作用。基于对手术病例的回顾性调查与分析,作者观察到,若仅考虑这一因素,它似乎并不会显著增加感染性并发症、吻合口裂开的发生率,也不会延长术后平均住院时间。研究人员对四组同质患者进行了检查。其中两组各有100例接受了未污染腹腔的腹部手术。另外两组各有150例接受了部分污染的结直肠手术。除抗生素预防措施外,患者的一般准备情况相似。通过分析麻醉记录来计算平均时间。从对最新数据的分析来看,这些数据的特点是没有吻合口裂开和手术死亡率,即便平均手术时间较长,败血症的发生率也已降至4%。术后平均住院时间也从17.3天缩短至13天。手术时间的延长并非取决于手术的复杂性、术中并发症或外科医生的经验不足,而可能是由于为预防并发症而精心实施的程序和步骤所致,鉴于这些操作需要极度谨慎和专注,必然会导致手术时间增加。关于抗生素预防和手术时长,研究发现,如果抗生素预防在手术前超过一小时进行,败血症的发生率约为20%。如果治疗与麻醉诱导或手术开始同时进行,那么败血症的发生率则降至13%。(摘要截选至250字)