聚乙二醇化血红蛋白使缺血大鼠肝脏模型中的氧张力恢复正常。
Normal oxygen tension restored in the ischemic rat liver model by PEG-hemoglobin.
作者信息
Linberg R, Johnson M, Nho K, Gilbert C, Shorr R
机构信息
Enzon, Inc., Piscataway, NJ 08854.
出版信息
Artif Cells Blood Substit Immobil Biotechnol. 1994;22(3):805-12. doi: 10.3109/10731199409117914.
PMID:7994403
Abstract
Cell damage initiated during ischemia, as a result of oxygen depletion, continues during reperfusion, and recovery is dependent on the length of the ischemic period. This study investigates the effect of polyethylene glycol-modified hemoglobin (PEG-Hb) on recovery of tissue oxygen tension after induced ischemia.
摘要
在缺血期间因氧耗竭引发的细胞损伤，在再灌注期间仍会持续，并且恢复情况取决于缺血期的时长。本研究调查了聚乙二醇修饰血红蛋白（PEG-Hb）对诱导缺血后组织氧张力恢复的影响。
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